- Sacha Boey
- Sadio Mané (Retired)
- Salem Al-Dawsari
- Salis Abdul Samed
- Salomón Obama
- Salvatore Sirigu
- Sam Campbell
- Sam Johnstone
- Sam Lammers
- Samer Al-Jundi
- Sami Khedira (Retired)
- Samir Handanović (Retired)
- Samir Maarouf
- Sammie Szmodics
- Sammy Ameobi
- Sammy Whiteside
- Samu Omorodion
- Samuel Chancely (Retired)
- Samuel Chukwueze
- Samuel Gomes (Retired)
- Samuel Lino
- Samuel Umtiti
- Sander Berge
- Sandro Tonali
- Santi Cazorla
- Santiago Arias
- Santiago Giménez
- Sardar Azmoun
- Saša Kalajdžić
- Sasha Marcich
- Saúl
- Savenaca Singh
- Sávio
- Scott Arfield
- Scott McTominay
- Scott Tanser
- Scott Wiseman
- Sead Kolašinac
- Sean Johnson
- Sean Longstaff
- Sean Pitts (Retired)
- Sebastián Coates
- Sebastián Driussi
- Sébastien Haller
- Seko Fofana
- Senad Lulić (Retired)
- Serge Aurier
- Serge Gnabry
- Sergej Milinković-Savić
- Sergi Darder
- Sergi Roberto
- Sergiño Dest
- Sergio Agüero (Retired)
- Sergio Asenjo
- Sergio Busquets
- Sergio Canales
- Sergio Gómez
- Sérgio Oliveira
- Sergio Ramos
- Sergio Reguilón
- Sergio Romero
- Serhou Guirassy
- Sezer Özbalta (Retired)
- Shane Duffy
- Shane Poggenpoel
- Shaquille Kocks
- Sheraldo Becker
- Shinji Kagawa
- Shola Adeyemo (Retired)
- Sikou Niakaté
- Silly Sangharé
- Silvano Vos
- Šime Vrsaljko
- Simon Adingra
- Simon Kjær
- Simon Novak-Liddle
- Simone Nelli (Retired)
- Skye Vink
- Sofyan Amrabat
- Sokratis Papastathopoulos
- Solly March
- Solomon One
- Son Heung-Min
- Sondre Rossbach
- Stanislav Lobotka
- Stefan de Vrij
- Stefan Posch
- Ştefan Radu
- Stefan Savić
- Stefano Sensi
- Steffan Klein (Retired)
- Stephan El Shaarawy
- Stephen Eustáquio
- Stephen Jones (Retired)
- Steve Mandanda
- Steven Berghuis
- Steven Bergwijn
- Stewart Downing (Retired)
- Strahinja Pavlović
- Stuart Dallas
- Sulley Muntari
- Suso
- Sven Botman
- Syed Quazem Alam
